Jordanka Gluhcheva

Institute of Experimental Morphology, Pathology and Anthropology with Museum IEMPAM-BAS
Department of Experimental Morphology

Phone: + 359 2 979 2344
E-mail: ygluhcheva@hotmail.com

Scientific degrees, institution, year:     PhD, IEMAM-BAS, 2006
Fields of Research:     Morphology, hematology, stem cells, in vivo and in vitro experimental models, metals

Recent Publications:

1. Ju. Ivanova, Y. Gluhcheva, K. Kamenova, S. Arpadjan, M. Mitewa. Tetraethylammonium salt of monensic acid – antidote for treatment of subacute cadmium intoxication. A study on ICR mice model. JTEMB, 2012 (in press)

2. Y. Gluhcheva, I. Ivanov, V. Atanasov, N. Antonova, Ju. Ivanova, M. Mitewa. Hematological changes in case of chronic cadmium intoxication and monensin detoxication. Relationship with rheological variables. Clin Hemor Mircrocir, 49(1), 2011, 417-422

3. N. Antonova, P.Riha, I. Ivanov, Y. Gluhcheva. Experimental evaluation of mechanical and electrical properties of RBC suspensions in Dextran and PEG under flow II. Role of RBC deformability and morphology. Clin Hemor Mircrocir, 49(1), 2011, 441-450

4. E. Zvetkova, N. Antonova, I. Ivanov, Y. Savov, Y. Gluhcheva. Platelet morphological, functional and rheological properties attributable to addictions. Clin. Hemorheol. Microcirc., 2010, 45(2-4), 245-51

5. K. Kurz, Y. Gluhcheva, E. Zvetkova, G. Konwalinka, D. Fuchs. Interferon-gamma-mediated pathways are induced in human CD34(+) haematopoietic stem cells. Immunobiology, 2010, 215, 452-457                   

6. Y. Gluhcheva, V. Atanasov, R. Zhorova, M. Madzharova, J. Ivanova, M. Mitewa. Cobalt bioaccumulation in mouse blood plasma and liver. Biotechnol. & Biotechnol., 2010, 311-314

7. M. Madzharova, Y. Gluhcheva, E. Pavlova, N. Atanassova. Effect of cobalt on male reproductive organs during puberty. Biotechnol. & Biotechnol., 2010, 321-324

8. N. Antonova, P. Riha, I. Ivanov and Y. Gluhcheva. Study of Rheological and Electrical Behaviour of RBC Suspensions in Dextran and PEG under Non-steady Flow. Role of RBC Deformability and Morphology, IFMBE Proceedings Series, vol.31, pp. 330-333, 2010, C.T. Lim and J.C.H. Goh (Eds.): , Springer.

9. N. Antonova, I. Ivanov, Y. Gluhcheva, E. Zvetkova. Rheological and electrical properties of RBC suspensions in dextran 70.  Changes in RBC morphology.  MEDICON 2010, IFMBE Proceedings Series, P.D. Bamidis and N. Pallikarakis (Eds.), Springer Verlag, 29, 2010, 647–650

10. Е.. Zvetkova, N. Antonova, I. Ivanov, Y. Savov, Y. Gluhcheva. Main hemorheological problems in disorders of social significance. Series on Biomechanics, 25, 2010, 1-2, 61-67

11. Y. Gluhcheva, M. Madzharova, V. Atanasov, R. Nizamova, M. Mitewa. Influence of cobalt (II) chloride on plasma iron level in mice. Series on Biomechanics, 25, 2010, 1-2, 147-149

12. Y. Gluhcheva, I. Ilieva. Influence of cobalt chloride on mouse peripheral blood cells. Acta morphol. et anthropol., 15, 2010, 67-69

13. Y. Gluhcheva, M. Madzharova, V. Atanasov, R. Zhorova, M. Mitewa, E. Pavlova, J. Ivanova. The affect of cobalt salts on some weight indices in developing mice. Acta morphol. et anthropol., 2010 (in press)

14.Y. Gluhcheva, D. Fuchs. Influence of cobalt chloride on biochemical parameters in blood sera. Trace Elements in the Food Chain. Deficiency or Excess of Trace Elements in the Environment as a Risk of Health. Budapest, Hungary, 2009, 422 – 426

15. Y. Gluhcheva. The influence of cobalt chloride on mouse bone marrow. J Biomed Clin Res Suppl. 1, vol. 2, No 1, 2009, 32-34

16. Y. Gluhcheva. Ineffective hematopoiesis in cases of myelodysplastic syndromes – the role of CD34+ stem and progenitor cells. Acta morphologica et anthropologica, 14, 2009, 147-151

17. Y. Savov, E. Zvetkova, I. Sainova, Y. Gluhcheva, N. Antonova, I. Ivanov, E. Bichkidjieva, I. Ilieva. Changes in leukocyte cytochemistry and hematometric indices in chronic heroin addicts. Acta morphologica et anthropologica, 13, 2008, 159-163

18.Y. Gluhcheva, E. Zvetkova, G. Konwalinka, D. Fuchs. IFN-γ-colony stimulating activity and in vitro effects on neopterin synthesis and tryptophan degradation. Acta morphologica et anthropologica, 13, 2008, 91-94

19. Y. Gluhcheva, K. Schroecksnadel, B. Wirleitner, E. Zvetkova, G. Konwalinka, D. Fuchs. Quantitative comparative analysis of the influence of IFN-γ on the erythroid (BFU-E and CFU-E) and myeloid (CFU-GM) progenitors in vitro. Acta morphologica et anthropologica, 12, 2007, 55-60

20. Y. Savov, N. Antonova, E. Zvetkova, Y. Gluhcheva, I. Ivanov, I. Sainova, E. Bichkidjieva, I. Ilieva. Changes in blood viscosity and erythrocyte indices in chronic heroin abusers. Acta morphologica et anthropologica, 12, 2007, 67-71

21. Y. Savov, E. Zvetkova, Y. Gluhcheva, I. Sainova, N. Antonova, I. Ivanov, I. Ilieva, E. Bichkidjieva. Thrombocyte count, platelet morphological properties and whole blood viscosity attributable to chronic heroin addiction. Proceedings of 2^nd EuroSummer School on Biorheology & Symposium on Microмechanobiology of Cells, Tissues and Systems, Varna, 2007, pp. 38-41

22. Y. Savov, N. Antonova, E. Zvetkova, Y. Gluhcheva, I. Ivanov, I. Sainova. Whole blood viscosity and erythrocyte hematometric indices in chronic heroin addicts. Clin. Hemorheol. Microcirc., 35, 2006, 1-2, 129-133   

23. Y. Gluhcheva, K. Schroecksnadel, B. Wirleitner, I. Ilieva, E. Bichkidjieva, B. Nikolov, E. Zvetkova, G. Konwalinka, D. Fuchs. The influence of interferon-gamma on the processes of proliferation and differentiation of hematopoietic CD34+ progenitor cells in human erythropoiesis. Acta morphologica et anthropologica, 11, 2006, 43-50

24. Y. Gluhcheva, E. Zvetkova, G. Konwalinka, D. Fuchs. Quantitative investigation of the in vitro influence of IFN-γ on hematopoietic colony formation by human CD34+ progenitor cells. Proceedings of International Conference Automatics and Informatics’06, САИ, 2006, 131-133

25. Y. Gluhcheva, K. Schroecksnadel, B. Wirleitner, E. Zvetkova, G. Konwalinka, D. Fuchs. Interferon-γ-stimulated neopterin production and tryptophan degradation by human CD34+ hematopoietic progenitor cells. Comp. Rend. Acad. Bulg. Sci., 58, 2005, 4, 445-450

26. Y. Gluhcheva, K. Schroecksnadel, B. Wirleitner, E. Bichkidjieva, I. Ilieva, E. Zvetkova, G. Konwalinka, D. Fuchs. The impact of human recombinant interferon-γ on the capacity of human CD34+ hematopoietic progenitor cells to differentiate in vitro into mature bone marrow macrophages. Acta morphologica et anthropologica, 10, 2005, 114-118

27. Y. Gluhcheva, E. Zvetkova, G. Konwalinka, D. Fuchs. IFN-γ-stimulated tryptophan degradation by human hematopoietic CD34+ progenitor cells. Proceedings of Balkan Scientific Conference of Biology, 2, 2005, 55-62 – разширен вариант на No 3.

28. I. Sainova, Y. Savov, Y. Gluhcheva, R. Toshkova, E. Bichkidjieva, E. Zvetkova. Evaluation of berberine as a DNA-specific fluorescent dye, antitumor-, antioxidant- and immunomodulatory drug. Experimental pathology and parasitology, 8, 2005, 1, 52-59

29. E. Zvetkova, Y. Savov, Y. Gluhcheva, E. Bichkidjieva, E. Katzarova, I. Ilieva, I. Tsenov. Human bone marrow granulocyte-macrophageal colonies (GM-Cs) in vitro: Myeloid cells in health and in cases of myeloid leukemia. Clin. Hemorheol. Microcirc., 30, 2004, 481-484

30. Y. Gluhcheva. Hematopoietic growth factors (mini-review). Acta morphologica et anthropologica, 9, 2004, 194-201

31. Y. Gluhcheva, S. Christova. Quantitative DNA analysis in dysplastic changes and carcinoma of the cervix uteri. Acta morphologica et anthropologica, 8, 2003, 148-150

32. Y. Gluhcheva, S. Christova. Evaluation of the quantitative cytological changes in the epithelium of the uterine cervix. CIT, 3, 2003, 1, 65-71

Recent Projects: DO 02 – 351/2008; DMU 03/25; DMU 03/18; DNTS/Macedonia 01/12

Membership: Bulgarian Anatomical Society; Bulgarian Society of Biorheology